Buy 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) or O-methyl-bufotenin is a psychedelic of the tryptamine class. It is found in a wide variety of plant species, and at least one toad species, the Sonoran Desert toad. Like its close relatives DMT and bufotenin (5-HO-DMT), it has been used as an entheogen in South America. Slang terms include Five-methoxy, The power, and Toad venom. This isn’t the psychedelic you remember from college. It isn’t an eight-hour marathon experience tripping through the woods like Alice. It’s fast-acting, short-duration sometimes lasting as briefly as seven minutes — and is a rocket-ship ride into the center of the cosmos. 5-MeO-DMT is a powerful, hallucinogenic tryptamine found in various plants used historically in the preparation of psychotropic snuffs.
- It has been used as a healing agent by South American shamans for thousands of years, partially due to its ability to occasion mystical-type experiences. While research into the drug is still limited, recent studies are backing up these ancient claims.
- In a survey of 362 adults, 80% of respondents reported improvements in anxiety and depression after using 5-MeO-DMT, as well as an increase in well-being and life satisfaction. More than that, improvements were directly related to the intensity of the mystical effects felt during the experience. Respondents that had intense mystical experiences also reported higher rates of the experience’s personal meaning and spiritual significance.
- The benefits of 5-MeO-DMT have also proven to be enduring in a recent preliminary study, 42 participants who took 5-MeO-DMT reported an increase in levels of life satisfaction and mindfulness as well as lower levels of depression and anxiety. The effects persisted for four weeks after the initial experience when a follow-up assessment was completed.
- One of the unique aspects of 5-MeO-DMT is the short duration of the experience compared to more common psychedelics, such as LSD and psilocybin. While research has shown that psychedelic-assisted psychotherapy can help people with a variety of psychological disorders, these sessions often require a 7 to 8-hour session. Because 5-MeO-DMT is short-acting and lasts just 30-90 minutes, it shows promise as an accompaniment to therapy sessions, which are typically 60 to 90 minutes.